The market for epilepsy medications was valued at approximately US$ 7,768.50 million in 2022 and is expected to grow to around US$ 10,705.48 million by 2030, reflecting a compound annual growth rate (CAGR) of 4.1% from 2022 to 2030.
The expansion of the epilepsy drugs market is largely fueled by the rising incidence of epilepsy and the growing elderly population.
Epilepsy is a neurological disorder characterized by recurrent seizures, impacting millions worldwide. Medications used to treat epilepsy, commonly referred to as anti-epileptic drugs (AEDs), play a crucial role in managing seizures effectively for those affected by the condition. For patients who do not respond to medication, alternative treatments such as surgical interventions or implanted devices may be considered to help control seizures.
Patent Expirations of Several Epilepsy Drugs Present Growth Opportunities
In the coming years, numerous patents for epilepsy medications are set to expire, which is likely to enhance the availability of generic alternatives, thereby reducing healthcare costs. This situation will create new opportunities for various stakeholders in the market. Below is a list of some notable drugs approaching patent expiration in the near future.
Company | Patent | Patent Expiration Date | Ingredient | Treatment |
Sumitomo Pharma Co | US9206135 | April 21, 2026 | ESLICARBAZEPINE ACETATE | Partial-onset Seizures Epilepsy |
GlaxoSmithKline | US7919115 | January 4, 2029 | LAMOTRIGINE | Epilepsy |
Ucb Inc | USRE38551 | March 17, 2022 | Lacosamide | Epilepsy and Partial-onset Seizures |
SK Biopharmaceuticals | US7598279 | October 30, 2027 | CENOBAMATE | Partial Epilepsies |
SUPERNUS PHARMS | US8877248 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US9555004 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US10314790 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US8663683 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US9622983 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US8298580 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US8992989 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US8889191 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US9549940 | November, 2027 | Sustained-release formulations of Topiramate | Epilepsy |
SUPERNUS PHARMS | US8298576 | April, 2028 | Sustained-release formulations of Topiramate | Epilepsy |
Insights Based on Treatment
The epilepsy medication market is categorized by treatment into first-generation, second-generation, and third-generation anti-epileptic drugs. As of 2022, the second-generation AEDs dominated the market share, while the third-generation AEDs are projected to experience the highest growth rate from 2022 to 2030. The second-generation AEDs encompass drugs such as felbamate, gabapentin, lamotrigine, levetiracetam, oxcarbazepine, pregabalin, rufinamide, stiripentol, tiagabine, topiramate, vigabatrin, and zonisamide. In regions like North America and Europe, zonisamide is also classified as a second-generation drug. The higher costs associated with second-generation AEDs compared to first-generation options pose a challenge for their inclusion in formularies. However, second-generation AEDs are favored for their improved side-effect profiles and reduced risk of teratogenic effects compared to their predecessors. Many first-generation and some second-generation AEDs are known to induce enzymes that can enhance the metabolism of various substrates processed by the cytochrome P450 enzyme, potentially diminishing the efficacy of the inducer.
Insights Based on Distribution Channels
The epilepsy drugs market is also segmented by distribution channels, which include hospital pharmacies, retail pharmacy stores, and other outlets. In 2022, hospital pharmacies accounted for the largest market share, while the retail pharmacy segment is expected to grow at the fastest rate from 2022 to 2030. Hospital pharmacies procure medications from various manufacturers and supply them for both outpatient and inpatient care. They typically stock critical therapeutic drugs used in fields such as cardiology, neurology, urology, pathology, hematology, and dermatology. Hospital pharmacies are vital components of the healthcare infrastructure, ensuring that epilepsy medications are readily available for patients, thus holding a significant portion of the epilepsy drug market.
Key sources consulted in the preparation of this report on the epilepsy drugs market include the World Health Organization (WHO), the Centers for Disease Control and Prevention (CDC), the National Center for Biotechnology Information (NCBI), as well as investor presentations and annual reports from market participants.