Frozen Tissues Samples Market Research Report and Outlook by 2028

The frozen tissue samples market is anticipated to grow significantly, reaching an estimated US$ 105,045.91 Thousand by 2028, up from US$ 44,399.07 Thousand in 2021. This growth represents a compound annual growth rate (CAGR) of 13.1% from 2021 to 2028.

This report outlines the prevailing trends in the market and identifies key factors contributing to its expansion. The increasing utilization of frozen tissue samples across various research and therapeutic domains, particularly in oncology, is a primary driver of market growth. The rising incidence of cancer has further propelled the demand for these samples. However, challenges related to the preservation and maintenance of frozen tissue samples pose a barrier to market advancement.

Biopsies, which involve the extraction of small tissue samples from tumors or masses, are crucial for diagnosing conditions such as cancer, infections, and other disorders. A specific type of biopsy known as a frozen section allows for rapid identification of tissue characteristics during surgical procedures. This technique, referred to as cryosection, utilizes a cryostat for the procedure and is predominantly employed in surgeries related to cancer. The ability to analyze frozen tissue samples enables surgeons to determine whether a tumor is malignant or benign and assess if it has metastasized, thereby informing surgical decisions.

In addition to identifying tumors, frozen tissue samples can confirm the presence of lesions or help in locating lesions in suspicious tissue areas. They are particularly valuable for determining the origin of tissues that are small and difficult to identify, such as parathyroid glands. Furthermore, these samples are instrumental in assessing whether tumors have spread to lymph nodes and nerves, and they can also be used to investigate distant organ metastasis.

Frozen tissue samples are preferred for various analytical techniques, including mass spectrometry, next-generation sequencing, western blotting for post-translational modifications, and quantitative real-time polymerase chain reaction (qRT-PCR). They are considered the gold standard for DNA and RNA sequencing when the strands exceed 50 base pairs. Additionally, frozen samples are advantageous in immunohistochemistry, as they preserve proteins in their native state.

Numerous research studies leverage frozen tissue samples across diverse therapeutic areas, including oncology, inflammation, and neurological diseases. For example, rheumatoid arthritis (RA), a chronic autoimmune condition characterized by joint inflammation, has been extensively studied using synovial tissue biopsies. These biopsies enhance understanding of disease mechanisms and aid in the discovery of new biomarkers and therapeutic targets. The examination of synovial tissue through frozen sections provides critical insights for diagnosing and treating RA.

Given that biological materials are often delicate and perishable, stringent measures are taken to ensure the preservation of frozen tissue samples. This careful handling is a significant factor driving the growth of the frozen tissue samples market.

In Canada, cancer is the leading cause of mortality, while in the United States, it ranks second after heart disease. The American Cancer Society estimates that in 2022, approximately 1.9 million new cancer cases will be diagnosed, with 609,360 deaths attributed to the disease. Prostate cancer is the most frequently diagnosed cancer among men in North America, while breast cancer remains the most prevalent among women. Lung cancer continues to be the leading cause of cancer-related deaths. The annual incidence rate of new cancer cases is estimated at 439.2 per 100,000 individuals. This increasing cancer prevalence is a significant factor contributing to the growth of the frozen tissue samples market globally.

The global market for frozen tissue samples is categorized by product type into frozen normal tissue samples, frozen tumor tissue samples, and frozen diseased tissue samples. In 2021, the frozen tumor tissue samples segment held the largest market share and is projected to exhibit the highest CAGR during the forecast period from 2021 to 2028, driven by the rising number of tumor cases worldwide.

By application, the market is divided into disease diagnosis and treatment, cancer and other disease research, and morphological analysis. The cancer and other disease research segment dominated the market in 2021, while the disease diagnosis and treatment segment is expected to experience the fastest growth, with a CAGR of 13.8% from 2021 to 2028.

Regarding end users, the frozen tissue samples market is segmented into hospitals and clinics, academic and research institutes, diagnostic centers, and others. The academic and research institutes segment held the largest market share in 2021, but the hospitals and clinics segment is projected to grow at the fastest rate, with a CAGR of 13.9%.

Key sources referenced in the preparation of this report include the National Center for Health Statistics, Central Drugs Standard Control Organisation, Centers for Disease Control and Prevention (CDC), National Institute of Statistics, Geography, and Informatics, German Biobank Alliance, National Health and Medical Research Council, and the World Health Organization.