The mesotherapy market size is expected to grow from US$ 664.13 million in 2024 to US$ 1,317.05 million by 2031; it is projected to register a CAGR of 10.4% during 2025-2031. Rising demand for non-invasive aesthetic procedures and technological advancements in mesotherapy devices and personalized treatments are noteworthy factors contributing to the expansion of the mesotherapy market size. However, lack of standardization and regulatory control hinders the mesotherapy market growth.

The integration of combination therapy that merges mesotherapy with other aesthetic treatments to achieve effective results is likely to emerge as a key future trend in the market. The shifting consumer expectations and clinical practices in the cosmetic business have propelled patients to demand multidimensional solutions that treat skin and well-being issues in one treatment plan. In the past, mesotherapy was applied as a single treatment consisting of microinjections of vitamins, peptides, or hyaluronic acid into the skin to rejuvenate and repair tissues. With advances in product formulation and clinical practice, it is combined with other treatments such as chemical peels, laser resurfacing, microneedling, platelet-rich plasma (PRP), and radiofrequency (RF) therapy.

Blending mesotherapy and PRP have become standard protocols in upscale clinics. PRP, which is taken from the patient's blood, comprises growth factors that stimulate healing and tissue regeneration. When applied in tandem with mesotherapy, the microchannels from the microneedling pen help the PRP and meso-cocktail penetrate deeper into the skin, maximizing the effects of both. This synergy is useful in hair restoration and facial rejuvenation procedures, where increasing collagen production and cell turnover are of the most value. Similarly, Mesobotox is a facial rejuvenation technique that involves injecting a highly diluted combination of botulinum toxin and a mesotherapy solution into the superficial layers of the skin. Unlike traditional Botox, which is administered directly into muscles to relax dynamic facial wrinkles, mesobotox uses a lower concentration of the toxin and targets the skin's surface rather than the underlying muscles. Owing to this gentle approach, natural facial expressions are maintained while delivering cosmetic benefits. Fine lines are softened, and patients often see a subtle lifting effect, along with reduced sebum production, sweating, and pore size in the treated areas. Mesobotox offers a refined, natural-looking result ideal for those seeking skin enhancement without altering facial movement, thereby emerging as a significant mesotherapy market trend in the coming years.

Route of Administration-Based Insights

Based on route of administration, the mesotherapy market is segmented into injectable and topical. The injectable segment held a larger mesotherapy market share in 2024. Injectables are widely used for facial rejuvenation, cellulite treatment, localized fat reduction, and hair transplantation. The popularity of injectable mesotherapy is driven by a surging demand for non-surgical cosmetic treatments, along with the preference for minimal downtime and natural-looking results. Injectable mesotherapy enables practitioners to provide customized treatments aimed at treating specific issues, thereby increasing patient satisfaction and service provision. A comparison study in 2019 involving mesotherapy (intralesional injection) versus topical 5% minoxidil for male androgenic alopecia revealed that mesotherapy resulted in increased hair shaft diameter, suggesting its possible efficacy in hair therapies, thereby fueling the mesotherapy market growth.

International Society of Aesthetic Plastic Surgery and the People Research on India's Consumer Economy are among the primary and secondary sources referred to while preparing the mesotherapy market report.