PCR Technology Market Size, Share, Growth by 2030

The PCR technologies market is projected to expand from US$ 13,101.87 million in 2022 to US$ 24,524.50 million by 2030, with an anticipated compound annual growth rate (CAGR) of 8.2% during the period from 2022 to 2030.

The growth of the PCR technologies market is significantly driven by the increasing incidence of genetic and infectious diseases, alongside rising investments and funding directed towards PCR technologies.

PCR plays a vital role in clinical environments, facilitating the swift and accurate identification of genetic variations, infectious diseases, and biomarkers. This widely used molecular biology technique, known as polymerase chain reaction (PCR), amplifies DNA and RNA sequences, which supports a variety of applications in research, diagnostics, and other fields. The demand for PCR-based diagnostics has surged due to the growing prevalence of chronic diseases and advancements in genomic research. Furthermore, the automation and integration of PCR instruments, along with continuous enhancements in reagents and software, have improved the performance, sensitivity, and efficiency of workflows, thereby contributing to market growth.

Increasing Incidence of Genetic and Infectious Diseases Fuels Market Growth

Data from the National Organization regarding genetic conditions indicates that while genetic disorders are generally rare, they collectively account for over 15,500 positive diagnoses annually. A report by MJH Life Sciences (US) in 2022 estimates that approximately 300,000 newborns worldwide are diagnosed with sickle cell disease (SCD) each year, representing about 5% of the global population. In the United States, SCD is one of the most common genetic disorders, with the Centers for Disease Control and Prevention (CDC) reporting that 1 in 500 African Americans is affected, and about 1 in 12 carries the autosomal recessive mutation. According to a June 2020 report by Novartis AG (Switzerland), around 15,000 individuals and 270 newborns are diagnosed with SCD annually, with the disease being particularly prevalent in developing countries like India. Among tribal communities in India, approximately 18 million individuals carry sickle cell traits, and 1.4 million are affected by SCD. Consequently, the rising incidence of SCD has led to an increased adoption of digital polymerase chain reaction (dPCR) in pathology centers, where this technology is utilized to target specific DNA sequences for diagnostic confirmation and the development of various clinical tests. dPCR is capable of identifying specific DNA sequences from a single DNA molecule, enabling researchers to detect rare genetic mutations that are challenging to identify using traditional real-time PCR methods.

The COVID-19 pandemic had a profound impact on the PCR technologies market. PCR is a widely utilized, robust, and reliable technology in molecular biology laboratories for amplifying specific DNA segments for genotyping, cloning, and analyzing single nucleotide variations. The amplified DNA serves as the foundation for most next-generation sequencing (NGS) preparations. Almost all diagnostic tests for COVID-19 relied on real-time PCR to test symptomatic individuals. Many biotech and pharmaceutical companies redirected their focus towards research and development to discover new compounds or therapeutic strategies for COVID-19, which positively influenced the PCR technologies market. In February 2022, Roche introduced the Cobas 5800 System, a new molecular laboratory instrument, to its COVID-19 PCR portfolio for use in countries that accept CE certification. This product line includes the Cobas SARS-CoV-2 and influenza A/B tests, as well as the Cobas SARS-CoV-2 qualitative test, providing consistent performance and efficiency across low-, medium-, and high-volume molecular laboratory tests.

Market Opportunities

The growing adoption of PCR techniques in emerging markets presents significant opportunities. In recent years, molecular methods like PCR have emerged as essential diagnostic tools, enabling healthcare professionals to accurately diagnose a range of infectious diseases. PCR is recognized as a crucial research and diagnostic instrument, facilitating early disease detection and playing a key role in disease management. The technique yields reproducible results that are comparable across laboratories and is globally accepted. Emerging countries are increasingly adopting PCR technologies. According to a 2016 World Health Organization report on establishing PCR laboratories in developing nations, WHO has provided technical support to set up PCR facilities in all 11 Southeast Asian countries. These laboratories have adopted various PCR technologies, including reverse transcriptase PCR (RT-PCR), multiplex PCR, real-time PCR, in-situ PCR, and dPCR, tailored to their specific needs. The application of PCR technologies is expanding in clinical microbiology, virology, parasitology, biotechnology, and related fields due to the method's rapid, simple, and highly specific screening capabilities. Thus, the PCR technologies market in developing regions is expected to witness substantial growth opportunities in the coming years.

The "Global PCR Technologies Market" is categorized based on technology, offerings, applications, end users, and geographical regions.

Technology-Based Insights

The PCR technologies market is divided into segments based on technology, including real-time PCR, conventional PCR, reverse transcription, digital PCR (dPCR), multiplex RT-PCR, hot start PCR, and others. The real-time PCR segment held the largest market share in 2022 and is projected to achieve a higher CAGR of 8.8% from 2022 to 2030.

Real-time PCR is a nuclear-based method for detecting specific genetic material in various diseases, including viral infections. It has become one of the most widely used techniques for gene quantification due to its dynamic range, exceptional sensitivity, sequence specificity, and the absence of post-amplification processing, which allows for increased sample throughput. Maximizing these benefits requires a comprehensive understanding of the various operational options available.

Offerings-Based Insights

In terms of offerings, the PCR technologies market is segmented into reagents and consumables, instruments, and software and services. The reagents and consumables segment accounted for a significant market share in 2022 and is expected to grow at a CAGR of 9.1% from 2022 to 2030.

Reagents and consumables are critical components of PCR processes, encompassing buffers, probes, enzymes, dyes, vials, kits, and panels. Numerous kits are available for applications such as gene expression analysis, SNP genotyping, and microRNA analysis. The increasing demand for early disease detection, widespread use of consumables and reagents, and the growing need for PCR in healthcare and research have significantly driven the growth of this segment. Major manufacturers in this segment include Thermo Fisher Scientific, Kaneka Eurogentec S.A., and QIAGEN. Frequent product launches, the rising acceptance of technological innovations, and the increasing availability of these products are also key factors contributing to the segment's growth.

Application-Based Insights

The PCR technologies market is categorized by application into gene expression analysis, genetic sequencing, genotyping, nucleic acid synthesis, standard validation, point-of-care diagnostic applications, environmental applications, and others. The gene expression analysis segment held the largest market share in 2022 and is projected to grow at a CAGR of 9.0% from 2022 to 2030.

Gene expression analysis investigates how genes are transcribed to produce functional gene products, including RNA species or proteins. Understanding gene regulation provides insights into normal cellular processes, such as differentiation, as well as abnormal or pathological processes. Researchers can conduct gene expression analysis at various regulatory levels, including transcriptional, post-transcriptional, translational, and post-translational modifications.

End User-Based Insights

The PCR technologies market is segmented by end users into hospitals and diagnostic centers, pharmaceutical and biotechnology companies, research laboratories and academic institutions, and others. The hospitals and diagnostic centers segment held the largest market share in 2022 and is expected to grow at a CAGR of 8.7% from 2022 to 2030.

Hospitals and diagnostic centers play a crucial role in the PCR technologies market. They serve as primary facilities for patients seeking advanced treatment under the supervision of skilled professionals. Various PCR technologies, such as dPCR and qPCR, provide high sensitivity and specificity, enabling early and accurate detection of pathogens, including bacteria, viruses, and fungi. Hospitals also offer advanced diagnostic and treatment options for both acute and chronic conditions, leading to a higher adoption of PCR techniques in these settings. Diagnostic laboratories are equipped with advanced technology that facilitates efficient workflow and sample management. Companies like Bio-Rad Laboratories, Inc., Fluidigm Corporation, Eppendorf, and Agilent Technologies, Inc. supply PCR devices tailored to the needs of hospitals and diagnostic centers.

Relevant sources such as the Food and Drug Administration, Pharmaceutical Research and Manufacturers Association, and Japan Bioindustry Association were consulted in the preparation of the PCR technologies market research report.

PCR Technology Market Size, Share, Growth by 2030

Increasing Incidence of Genetic and Infectious Diseases Fuels Market Growth

Market Opportunities

Technology-Based Insights

Offerings-Based Insights

Application-Based Insights

End User-Based Insights

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LIST OF TABLES

LIST OF FIGURES

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