Solvent Evaporation Market Size, Trends and Growth Analysis by 2027

The solvent evaporation market was valued at approximately US$ 470.77 million in 2020 and is anticipated to grow to US$ 821.41 million by 2028, reflecting a compound annual growth rate (CAGR) of 6.7% from 2021 to 2028.

Several factors contribute to this market expansion, including increased investment in research and development (R&D), the rising production of large-molecule biopharmaceuticals, and a heightened demand for high-purity samples across various end-use sectors. Nevertheless, challenges such as inaccuracies in results and resource wastage due to the complexities associated with solvent evaporation may impede market progress.

Solvent evaporation is a process that entails the emulsification of polymers within an aqueous phase, followed by dispersion in a volatile solvent such as dichloromethane, chloroform, or ethyl acetate. The subsequent evaporation of the solvent can be achieved through methods like applying high temperatures, utilizing vacuum conditions, or maintaining continuous stirring. The size of the resulting particles can be finely tuned by adjusting various parameters, including the evaporation temperature, the rate of evaporation, and the stirring speed. This technique is commonly employed in the production of nanoparticles using specific polymers such as PLA, PLGA, PCL, and polyhydroxybutyrate, which are often loaded with drugs like tetanus toxoid, testosterone, loperamide, cyclosporin A, and indomethacin. Solvent evaporators are integral to processes like microencapsulation and are essential for preparing polymeric nanoparticles for a variety of pharmaceutical formulations. Recent technological advancements in solvent evaporation systems, including centrifugal concentration, freeze-drying, and high-power cold traps, have significantly improved evaporation efficiency and solvent recovery while minimizing environmental impact.

The global solvent evaporation market is categorized by type into several segments: rotary evaporators, nitrogen blowdown evaporators, centrifugal evaporators, and spiral air flow evaporators. In 2020, the rotary evaporators segment commanded the largest market share. However, the nitrogen blowdown evaporators segment is projected to experience the highest CAGR of 7.4% during the forecast period. Rotary evaporators are crucial for the effective extraction of solvents through evaporation, a vital step in producing pure samples across multiple industries. The growth of the solvent evaporation market is being driven by increasing R&D investments and the numerous advantages associated with this technique.

From an end-user perspective, the global solvent evaporation market is divided into segments including the pharmaceutical and biopharmaceutical industry, diagnostic laboratories, and research and academic institutions. The pharmaceutical and biopharmaceutical industry segment held the largest market share in 2020. However, the research and academic institutions segment is expected to achieve the highest CAGR of 7.7% during the forecast period, driven by factors such as the growing number of drug development studies and an increasing demand for ongoing innovation and enhancement of existing products.

Key organizations and sources that have been referenced in the preparation of the report on the solvent evaporation market include the Pharmaceuticals Research and Manufacturers Association, Health and Medicine Division, World Health Organization, and the American Association of Healthcare Administrative Management (AAHAM).