Cerebral Aneurysm Clips Market for Phynox Segment to Grow Significantly During 2022-2028

According to our latest study on ""Cerebral Aneurysm Clips Market Forecast to 2028 - COVID-19 Impact and Global Analysis - by Material Type, Indication, Condition, and End User,” the market is expected to grow from US$ 53,810.74 thousand in 2021 to US$ 81,960.78 thousand by 2028; it is estimated to grow at a CAGR of 6.3% from 2022 to 2028. The report highlights trends prevailing in the market and factors governing the market growth. The increasing prevalence of brain aneurysms and associated risk factors, and a surge in research and development activities for treating cerebral aneurysms drive the market growth. However, the high cost of surgical procedures may hinder the growth of the cerebral aneurysm clips market.

Increasing Prevalence of Brain Aneurysms and Associated Risk Factors:

A brain aneurysm or cerebral aneurysm is the development of a bulge in the brain's blood vessels. The bulge puts pressure on the nerves or brain tissues, and rupture or burst can cause brain bleeding, which can be fatal to a patient. Factors such as genetic conditions, arteriovenous malformations, untreated high blood pressure, and smoking cause brain aneurysms.

The growth of the cerebral aneurysm clips market is prominently attributed to the increasing prevalence of brain aneurysm cases worldwide. The increasing number of diagnostic procedures associated with the brain is also contributing to market growth. According to data published by the Brain Aneurysm Foundation in 2020, ~6.5 million people in the US, i.e., 1 in 50 persons, suffer from an unruptured brain aneurysm every year. Moreover, ~30,000 suffer a cerebral aneurysm rupture yearly, indicating that a cerebral aneurysm ruptures every 18 minutes. According to the Brain Aneurysm Foundation data, ~40.0% of ruptures are fatal, and need intensive care and attention. According to studies conducted by the National Institutes of Health (NIH), ~3-5% of Americans might have an aneurysm in their lifetime. Per the National Library of Medicine information, 2022, the global prevalence of cerebral aneurysms is ~3.2%, with a mean age of 50 and an overall 1:1 gender ratio; this ratio changes significantly among the people of age 50 and above to reach 2:0, with the predominance of females. The rate of rupture causing subarachnoid hemorrhage (SAH) is ~10 per 100,000, which may be greater in Finnish and Japanese populations, among others.

Clipping is performed during an open brain surgery to cut the blood flow to the aneurysm. This is done by locating the blood vessels that feed the aneurysm and placing a tiny, metal, clothespin-like clip on its neck to stop its blood supply. The effectiveness of clipping depends on the location, size, and shape of the aneurysm. As per the information provided by the National Library of Medicine in 2022, rupturing a cerebral aneurysm may accelerate mortality as ~25% die within the first 24 hours, and 50% die in the subsequent three months.

Further, an increasing commonness of risk factors associated with cerebral aneurysms-smoking, insomnia, and high blood pressure-are anticipated to drive the market growth.

•    According to a 2021 research study funded by the British Heart Foundation UK, smoking, insomnia, and high blood pressure are major risk factors for cranial aneurysm and aneurysmal SAH.

•    According to the data published by the Centers for Disease Control and Prevention (CDC) in 2018, ~14 of 100 people in the US smoke cigarettes. Apart from smoking and tobacco consumption, hypertension is another prominent factor raising the prevalence of cerebral aneurysms. According to World Health Organization (WHO), in 2019, ~1.13 billion people worldwide suffered from hypertension.

•    As per the study conducted at Case Western Reserve University, Ohio, US, in 2022, which compared the demographics and occurrence of hypertension in 20,767 Medicare patients with an unruptured aneurysm to a random sample of the hospitalized Medicare population, the prevalence of hypertension in patients with unruptured aneurysms was 43.2%, while it was 34.4% in the random sample. Further, a strong positive association between high blood pressure and aneurysmal SAH was observed in the prospective cohort study of 74,977 participants (Nord-Trøndelag Health study), 2021.

•    According to the research study titled ""Estimating the Global Incidence of Aneurysmal Subarachnoid Hemorrhage: A Systematic Review for Central Nervous System Vascular Lesions and Meta-Analysis of Ruptured Aneurysms,"" 2018, ~500,000 individuals in the world are likely to suffer from SAH each year, and low- and middle-income countries are likely to account for almost two-thirds of this number.

Material Type-Based Insights

Based on material type, the cerebral aneurysm clips market has been categorized into pure titanium and titanium-based alloys, cobalt-chromium-based alloys, phynox, and others. The pure titanium and titanium-based alloys segment held the largest share of the market in 2021; however, the phynox segment is expected to register the highest CAGR in the cerebral aneurysm clips market during 2022-2028.

Indication-Based Insights

The cerebral aneurysm clips market, based on indication, is segmented into saccular aneurysm, fusiform aneurysm, and mycotic aneurysm. The saccular aneurysm segment held the largest share of the market in 2021, and the mycotic aneurysm is anticipated to register the highest CAGR in the market during 2022-2028.

Condition-Based Insights

The cerebral aneurysm clips market, by condition, is bifurcated into unruptured aneurysm and ruptured aneurysm. In 2021, the unruptured aneurysm segment held a larger share of the market. However, the cerebral aneurysm clips market for the ruptured aneurysm segment is expected to grow at a faster CAGR during 2022-2028.

End User-Based Insights

Based on end user, the cerebral aneurysm clips market is segmented into hospitals, neurology centers, and ambulatory surgical centers, and others. In 2021, the hospitals segment held the largest share of the market. However, the neurology centers segment is expected to register the highest CAGR in the cerebral aneurysm clips market from 2022 to 2028.    

B. Braun Melsungen AG; Peter Lazic GmbH; Mizuho Medical Co. Ltd; Rebstock Instruments GmbH; KLS Martin Group; Integra Lifesciences Corporation; Ortho-Medical GmbH; and Adeor Medical AG are among the leading companies operating in the cerebral aneurysm clips market.

The report segments the cerebral aneurysm clips market as follows:

Based on material type, the cerebral aneurysm clips market is categorized into pure titanium and titanium-based alloys, cobalt-chromium-based alloys, phynox, and others. The market, by indication, is segmented into saccular aneurysm, fusiform aneurysm, and mycotic aneurysm. By condition, the cerebral aneurysm clips market is bifurcated into unruptured aneurysm and ruptured aneurysm. Based on end user, the market is segmented into hospitals, neurology centers, ambulatory surgical centers, and others. Based on geography, the cerebral aneurysm clips market is segmented into North America (US, Canada, and Mexico), Europe (France, Germany, UK, Spain, Italy, and Rest of Europe), Asia Pacific (China, India, Japan, Australia, South Korea, and Rest of Asia Pacific), the Middle East & Africa (Saudi Arabia, UAE, South Africa, and Rest of Middle East & Africa), and South & Central America (Brazil, Argentina, and Rest of South & Central America).

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