Mice Model Market for Inbred Mice Segment to Grow Significantly During 2022-2028

According to our latest study on "Mice Model Market Forecast to 2028 - COVID-19 Impact and Global Analysis - by Type, Service, Technology, Indication, End User, Application, and Mode," the market is expected to grow from US$ 1,705.70 million in 2022 to US$ 2,340.90 million by 2028; it is estimated to grow at a CAGR of 5.4% from 2022 to 2028. The report highlights trends prevailing in the market and factors governing the market growth. Increased use of mice models in virology, infectious disease, and others; the rising demand for personalized medicine; and increased R&D activities are driving the mice model market. However, the stringent regulations and laws for the ethical use of animals in research are hindering the market growth.

Growing Usage of Mice Models in Virology and Infectious Diseases

Mice models are essential tools to study the pathogenesis of infectious diseases and for the preclinical evaluation of vaccines and therapies against various human pathogens. The use of genetically defined inbred mouse strains, humanized mice, and gene knockout mice has enabled the research community to study the process of the way pathogens cause diseases, the role of specific host genes in controlling or promoting disease, and potential targets for prevention or identification of treatment for a variety of infectious agents. With the emergence of new infectious diseases, the animal model has become a vital tool for studying disease mechanisms and developing therapeutics. Mice with xenografted human immune systems have been used to study the pathogenesis of various infectious agents, including Plasmodium falciparum (malaria), Mycobacterium tuberculosis, dengue virus, and influenza virus. These models have been beneficial for studying HIV, including analyzing viral and host factors that promote viral replication, HIV interactions with the host's immune response, and as platforms for testing therapeutic approaches to control or cure HIV infection. Mice models are an essential resource for studying the mechanisms underlying infectious disease pathogenesis and as platforms for testing potential vaccines and therapies. Mice models are necessary for learning about infections from many human pathogens. They are widely used for preclinical screening of vaccines/therapies because of their high reproducibility, low cost, and ease of experimental manipulation.

Over the past century, advances in the development of vaccines, antibiotics/antivirals, and infection control measures have significantly reduced the public health burden of infectious diseases. However, there has been an increase in contagious viral diseases over the years. In the past two decades, there have been three outbreaks of COVID-19-SARS-CoV in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019. However, the current SARS-CoV-2 is much more severe than the SARS-CoV in 2002 and has spread to more than 213 countries, affecting millions of people. The emergence of the COVID-19 pandemic in 2019 has prompted animal models to study its pathology and develop an effective treatment. Aside from coronavirus studies, mice models are considered the best small animal models for hepatitis B virus (HBV), hepatitis C virus (HCV), Zika virus, and cytomegalovirus (CMV). According to the WHO, over 17 million people die from infectious diseases yearly. Over the past two decades, over 30 new infectious diseases have emerged. As per the UNAIDS, 38 million people were affected by HIV at the end of 2019. Mice models have been widely used for various viral studies due to their small size, low cost, ease of use, and high reproducibility. Thus, the growing number of infectious disease is driving the mice model market.

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Type-Based Insights

Based on type, the mice model market is categorized into inbred mice, outbred mice, genetically engineered mice, hybrid mice, surgically modified mice, and spontaneous mutant mice. The inbred mice segment is expected to account for the largest share of the market in 2022. However, the genetically engineered mice segment is expected to register the highest CAGR during the forecast period.

Service-Based Insights

Based on service, the mice model market is segmented into breeding, cryopreservation, model-in licensing, genetic testing, quarantine, and others. The breeding segment is expected to account for the largest share in 2022 and is anticipated to grow at the highest CAGR from 2022 to 2028.

Technology-Based Insights

Based on technology, the mice model market is categorized into CRISPR, microinjection, embryonic stem cell injection, nuclear transfer, and others. The CRISPR segment is expected to account for the largest share of the mice model market in 2022. However, the microinjection segment is anticipated to grow at the highest CAGR from 2022 to 2028.

Indication-Based Insights

Based on indication, the mice model market is segmented into oncology studies, immunology & inflammation studies, endocrine metabolic studies, cardiovascular studies, central nervous system studies, genetic studies, infectious disease studies, fibrosis, and other disease studies. The oncology studies segment is expected to account for the largest market share in 2022 and is anticipated to grow at the highest CAGR during the forecast period.

Mode-Based Insights

Based on mode, the mice model market is bifurcated into in-house and outsourced. In 2022, the outsourced segment held a larger share of the mice model market. However, the in-house segment is expected to register a higher CAGR from 2022 to 2028.

End User-Based Insights

Based on end user, the mice model market is segmented into academic & research institutes, pharmaceutical & biotechnology companies, contract research organizations, and others. In 2022, the academic and research institutes segment held the largest share of the market and is expected to register the highest CAGR from 2022 to 2028.

Charles River Laboratories; The Jackson Laboratory; Taconic Biosciences, Inc; TRANS GENIC INC.; GenOway S.A.; Envigo; Janvier Labs; Ozgene Pty Ltd.; Crown Bioscience Inc.; and Harbour BioMed are among the leading companies operating in mice model market.

The report segments the mice model market as follows:

Based on type, the mice model market is categorized into inbred mice, outbred mice, genetically engineered mice, hybrid mice, surgically modified mice, and spontaneous mutant mice. Based on service, the market is segmented into breeding, cryopreservation, model-in licensing, genetic testing, quarantine, and others. Based on technology, the market is segmented into CRISPR, microinjection, embryonic stem cell injection, nuclear transfer, and others. Based on indication, the market is categorized into oncology studies, immunology & inflammation studies, endocrine metabolic studies, cardiovascular studies, central nervous system (CNS) studies, genetic studies, infectious disease studies, fibrosis, and other disease studies. Based on application, the market is segmented into preclinical drug development, biomarker analysis, and basic cancer research. Based on mode, the market is bifurcated into in-house and outsourced. Based on end user, the mice model market is segmented into academic & research institutes, pharmaceutical & biotechnology companies, contract research organizations, and others. By geography, the market is segmented into North America (the US, Canada, and Mexico), Europe (France, Germany, the UK, Spain, Italy, and the Rest of Europe), Asia Pacific (China, India, Japan, Australia, South Korea, and the Rest of APAC), the Middle East & Africa (Saudi Arabia, the UAE, South Africa, and the Rest of MEA), and South & Central America (Brazil, Argentina, and the Rest of SAM).

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